Fentanyl Withdrawal Symptoms and Timeline: What You Need to Know

Call Atlas Behavioral Health Now For Experiential Therapy

Call today and talk to our team.

For many, the thought of stopping fentanyl is more frightening than continuing its use. People often hesitate because they don’t know what withdrawal feels like or how long it will last. That uncertainty can keep them stuck in a painful cycle.

At Atlas Behavioral Health, we believe that knowledge takes away some of that fear. By understanding the withdrawal process, you can prepare for what’s ahead, and, most importantly, recognize that you don’t have to go through it alone.

Why Fentanyl Withdrawal Feels Different

Fentanyl is one of the most powerful opioids in circulation. Its strength is estimated to be 50 to 100 times greater than morphine, which means dependence forms quickly. Even a short period of use can cause significant changes in the brain and body.

Withdrawal from fentanyl isn’t just physical. Yes, the body craves the drug once it’s gone, but the emotional crash that follows can be just as overwhelming. That dual impact is why professional support is often essential for a safe and successful recovery.

What Happens in the Body During Withdrawal?

Opioids like fentanyl work by attaching to receptors in the brain and nervous system that control pain, mood, and reward. Over time, the body adjusts to the constant presence of the drug. When fentanyl use suddenly stops, those receptors are left unbalanced.

That imbalance causes withdrawal symptoms: the body essentially “relearning” how to function without fentanyl. This process is uncomfortable, but it’s also a sign that the body is healing and beginning to restore its natural rhythm.

Early Withdrawal Symptoms

The First 24–48 Hours

These symptoms may feel similar to the flu, but with an added layer of emotional distress. Sleep can be difficult, and cravings often emerge quickly.

  • Muscle aches and restlessness
  • Anxiety and irritability
  • Runny nose and watery eyes
  • Sweating and yawning
  • Insomnia begins

Peak Withdrawal: When Symptoms Intensify

By the second to fourth day, withdrawal typically reaches its most difficult stage. Nausea, vomiting, and diarrhea are common. Many people report intense chills, hot flashes, and uncontrollable shaking.

Emotionally, this stage is often marked by heightened anxiety, rapid mood swings, and deep frustration. Cravings can feel overwhelming, making it one of the riskiest times for relapse. This is also when having medical and emotional support makes the biggest difference.

Late Withdrawal Symptoms

After about a week, physical discomfort usually begins to fade. Appetite may slowly return, and the body starts regaining strength. But this doesn’t mean the journey is over.

Emotional challenges often linger well beyond the physical symptoms. Many people experience fatigue, depression, or ongoing anxiety. Some face post-acute withdrawal syndrome (PAWS), a period of mood swings, sleep issues, and cravings that can last weeks or even months. Recognizing this stage helps individuals plan for long-term recovery strategies.

The Role of Mental Health in Withdrawal

For many, fentanyl use is tied to deeper struggles such as trauma, anxiety, or depression. When the drug is removed, these underlying conditions can surface in full force. That’s why treating fentanyl withdrawal requires more than just managing physical symptoms.

At Atlas Behavioral Health, we specialize in dual diagnosis treatment, addressing both substance use and mental health at the same time. By treating the whole person, mind and body, we help clients build the resilience needed to move forward.

Medical Detox vs. Going It Alone

Some people attempt to detox from fentanyl at home, hoping privacy will make it easier. In reality, this approach often increases risk. Severe withdrawal symptoms can be dangerous if left unmanaged, and the intensity of cravings often leads to relapse before detox is complete.

By contrast, professional detox offers a safer, more compassionate path. Medical teams can monitor vital signs, provide medication support when necessary, and ensure comfort throughout the process. Just as important, clients receive encouragement and emotional care that helps them keep moving forward even during the hardest days.

What to Expect in a Professional Setting

At Atlas Behavioral Health, withdrawal support goes beyond keeping people physically stable. Clients can expect:

  • 24/7 monitoring for safety so that any complications are addressed immediately.
  • Comfort-focused care to ease the most difficult symptoms.
  • Therapeutic support that begins the emotional healing process alongside detox.
  • Preparation for the next level of care, such as PHP or IOP, ensuring continuity after detox ends.

This step-down approach gives people structure and stability as they begin adjusting to life without fentanyl.

Fentanyl withdrawal can feel like standing at the base of an impossible mountain. The symptoms are real, and the timeline can be tough. But with the right support, each stage becomes more manageable, and every day brings you closer to healing.

At Atlas Behavioral Health, we provide the safety, compassion, and structured care you need to move through withdrawal and into long-term recovery.

Reach out to Atlas Behavioral Health today and begin your path toward healing in a safe and supportive environment.

FAQs

How long does fentanyl withdrawal last?

Most people experience acute symptoms for 7–10 days, though emotional symptoms can persist for weeks or months.

Is fentanyl withdrawal life-threatening?

While withdrawal itself is usually not fatal, complications like dehydration, heart stress, or relapse risks can make unsupervised detox dangerous.

Can medication help with symptoms?

Yes. Certain medications can reduce cravings, manage discomfort, and improve the chances of a safe detox. These are only available in a supervised setting.

What happens after detox is complete?

Detox is the first step, not the end. Continued care, through programs like PHP, IOP, or outpatient therapy, helps individuals maintain progress and prevent relapse.

FAQ

Frequently Asked Questions

What types of therapy do you offer?

We believe in a personalized, holistic approach to wellness! We utilize many different treatment modalities, combined with the power of the 12 Steps to support you in achieving your goals. We offer three different levels of care, and make recommendations based on individual needs.

We believe in a personalized, holistic approach to wellness! We utilize many different treatment modalities, combined with the power of the 12 Steps to support you in achieving your goals. We offer three different levels of care, and make recommendations based on individual needs.

We believe in a personalized, holistic approach to wellness! We utilize many different treatment modalities, combined with the power of the 12 Steps to support you in achieving your goals. We offer three different levels of care, and make recommendations based on individual needs.

We believe in a personalized, holistic approach to wellness! We utilize many different treatment modalities, combined with the power of the 12 Steps to support you in achieving your goals. We offer three different levels of care, and make recommendations based on individual needs.

We believe in a personalized, holistic approach to wellness! We utilize many different treatment modalities, combined with the power of the 12 Steps to support you in achieving your goals. We offer three different levels of care, and make recommendations based on individual needs.

We believe in a personalized, holistic approach to wellness! We utilize many different treatment modalities, combined with the power of the 12 Steps to support you in achieving your goals. We offer three different levels of care, and make recommendations based on individual needs.

Related Articles

Why DBT in Atlanta, GA Is Trusted for Emotional Wellness

The Complete Guide to LGBTQ+ Therapy Services, Who They Support, and Why They Matter

Why LGBTQ+ Addiction Treatment in Atlanta Requires Affirming and Specialized Care

Initiate your voyage towards positive transformation

Connect with us today to begin your journey.

Verify Your Insurance & Get Access To Treatment

You can get insurance coverage in as little as 5 minutes!

Josh Camadeca, CARES, CPS-AD, CPS-MH, RCP, CIT (he/him)

Program Director

Josh Camadeca serves as the Program Director at Atlas Behavioral Health, where he oversees organizational workflows, supports program development, and ensures high-quality service delivery across clinical and peer-support departments. In this leadership role, Josh applies both his administrative expertise and his extensive recovery knowledge to strengthen team coordination, improve client care systems, and uphold the agency’s mission of providing accessible, person-centered behavioral health services. Josh is a Certified Addiction Recovery Empowerment Specialist (CARES), a Certified Peer Specialist in Addictive Diseases (CPS-AD), a Certified Peer Specialist in Mental Health (CPS-MH), and a nationally Certified Recovery Coach Professional (RCP). He is currently working on obtaining his Certified Addiction Counseling (CAC) certification through the Georgia Addiction Counselors Association (GACA). With over a decade in sustained recovery from substance use and more than 25 years of personal engagement with mental health therapy, he integrates lived experience with evidence-based recovery support to provide comprehensive peer-driven care. In his direct client work, Josh specializes in recovery coaching and mentoring, supporting individuals in developing personalized pathways to health, wellness, and long-term recovery. He is highly skilled in connecting clients and families with appropriate resources, recovery communities, and supportive services that enhance continuity of care and foster positive treatment outcomes. His clinical focus emphasizes recovery-oriented systems of care, the power of social connection, and the vital role of community integration. Josh’s strengths center on his ability to build trust, empathy, and empowerment within the therapeutic relationship. He is deeply committed to promoting resilience and helping clients move toward meaningful, self-directed lives in recovery. Outside of his professional work, Josh values healthy leisure and community engagement; his interests in hiking, biking, fitness, sports, and collecting sneakers and streetwear often serve as additional pathways for rapport-building and connection with individuals from diverse cultural backgrounds.

Julie River, M.S., LPC, NCC, CPS-MH, RCP, EMDR Trained (she/her)

Clinical Director

Clinical Director Julie River is the Clinical Director at Atlas Behavioral Health, where she provides leadership in clinical programming, staff development, and evidence-based service delivery. She is a Licensed Professional Counselor (LPC), National Certified Counselor (NCC), Certified Peer Specialist in Mental Health (CPS-MH), Recovery Coach Professional (RCP), and an EMDR-trained psychotherapist. Julie earned her Bachelor of Science in Human Services from Kennesaw State University and her Master of Science in Clinical Mental Health Counseling from Capella University. She specializes in the treatment of trauma, addictions, adoption-related issues, and identity development. Her clinical approach is postmodern, inclusive, and affirming, with a strong emphasis on the intersectionality of identity and culture. She integrates holistic and systems-based frameworks into her therapeutic modalities, supporting clients in developing deep self-understanding rooted in their formative experiences. With over a decade of experience across the continuum of care, Julie has worked in psychiatric hospitals, wilderness therapy programs, art therapy initiatives, outpatient treatment for addictions and eating disorders, trauma-focused therapy, private practice, and peer support. This diverse background informs her vision for Atlas: to provide evidence-based, client-centered, culturally competent, and identity-affirming care. She is equally committed to the wellbeing of the clinical team, recognizing that staff wellness directly impacts the quality of client care. Julie is passionate about psychology, neurobiology, and sociology, and actively pursues ongoing professional development in these fields. Outside of her clinical work, she enjoys training for marathons and ultramarathons, international travel, and exploring new cultures through hiking and meaningful connection with others.